Study of qualitative and quantitative indicators of the «Suttigen-2» capsule obtained on the basis of a domestic substance
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DOI:
https://doi.org/10.32523/2616-6771-2022-141-4-19-26Keywords:
hepatoprotectors, medicinal preparations, tannins, flavonoids, permanganatometry, complexometry, spectrophotometryAbstract
The article considers the problem of the production of drugs with hepatoprotective properties and the study of their physico-chemical properties. The quality of medicines has been established and control is strictly regulated in accordance with regulatory and technical documents.
The relevance of this work is due to the fact that external changes in drugs and the formation of toxic decomposition products in chemical research, the study of stability, and shelf life require consideration as a factor in the quality of medicines. Medicines are stored and transported in conditions that ensure the preservation of their quality and effectiveness. These conditions are fulfilled in accordance with regulatory documents. Qualitative reactions were carried out to determine the group of tannins and flavonoids. The indicators of uniformity of mass, decomposition, and solubility of capsules, humidity, acidity, and amount of peroxide were determined. Permanganometric, complexometric, spectrophotometric, and HPLC methods are used for quantitative analysis of the capsule composition.